Suggested Use: Take 1 softgel per day with a meal, or as directed by a health professional.
What Is It?
Ubiquinol is the active antioxidant form of CoQ10. It has an additional two hydrogen atoms and compromises the majority of the ubiquinone/ubiquinol pool in the plasma of healthy young subjects. In the body, the enzymatic conversion of ubiquinone to ubiquinol in the mitochondria is a key step in the electron transport chain and the manufacture of ATP.*
Uses For Ubiquinol-QH
Ubiquinol makes up over 90% of the CoQ10 found in the plasma of healthy young individuals, typically up to the age of about 40-45 years. This makes ubiquinol especially important for older individuals, individuals who may be experiencing greater levels of oxidative or physical stress, or individuals who appear not to respond to regular CoQ10 supplementation (possibly due to poor conversion of CoQ10 to ubiquinol in the body). Research suggests that it may be more readily absorbed than the ubiquinone form. The safety and bioavailability of ubiquinol were evaluated after single oral dose and 4-week multiple dose studies. Significant gastrointestinal absorption was observed and no clinically significant adverse effects were noted.*
In a preliminary case report involving an open clinical evaluation using ubiquinol, a U.S. cardiologist reports that plasma CoQ10 levels doubled for one 52 year-old woman after supplementation with 300 mg ubiquinol in divided doses for one month. It was also noted that ubiquinol supported a healthy ratio of CoQ10 to lipids. In a separate case, a 65 year-old male not responding to CoQ10 supplementation experienced a 4-fold increase in plasma CoQ10 after supplementation with the same dose of ubiquinol. In addition, ubiquinol supported healthy ejection fraction and mitral valve function while supporting overall physical activity and quality of life.*
What Is The Source?
CoQ10 is produced by microbial (yeast) fermentation. There is no residual yeast in the final product. Medium chain triglycerides are derived from palm oil. Gelatin is bovine-derived. Lecithin is derived from sunflower. Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil. Kaneka QH™ is a trademark of Kaneka Corporation. The use of ascorbyl palmitate in the formulation is covered by U.S. Patent 6,740,338.
Pure Encapsulations recommends 1–2 softgels daily with meals.
Are There Any Potential Side Effects Or Precautions?
Rarely, CoQ10 may cause mild gastrointestinal upset, nausea, vomiting, diarrhea or constipation. If pregnant or lactating, consult your physician before taking this product.
Are There Any Potential Drug Interactions?
CoQ10 may be contra-indicated for individuals taking blood thinning medication. Consult your physician for more information.